1995 Winners

Grand prize: Dr. Hengartner

Dr. Hengartner was born in St.-Gallen, Switzerland, but grew up in Paris, France; Bloomington, Indiana; and more recently QuŽbec City, Canada. After an initial foray into physics, he turned to biochemistry and started his research career in the laboratory of Guy Poirier at Laval University investigating polyADP ribosylation. His Ph.D. was awarded in 1994 by MIT for research performed in the laboratory of Robert Horvitz. He subsequently moved to the Cold Spring Harbor Laboratory as an independent staff member, where he has a laboratory in the space previously occupied by Barbara McClintock. His present research continues his work on the function of ced-9 in C. elegans and its upstream regulators and downstream targets.

Europe: Lauri A. Aaltonen

Lauri A. Aaltonen, for his essay "Molecular Genetic Background of Hereditary Nonpolyposis Colorectal Cancer," which is based on work performed in the Department of Medical Genetics, Haartman Institute, University of Helsinki, Finland, for his Ph.D. He received his M.D. from the University of Helsinki and continues his work on colon cancer genetics in the Haartman Institute.

North America: Fiona Topfer

Fiona Topfer, presently investigating autoimmune disease in the Laboratory of Immunology, National Institute of Arthritis and Infectious Diseases, the National Institutes of Health, Bethesda, Maryland, for her essay "Tolerance and Immunity of La and Ro." She obtained her B.S. from the Australian National University and her Ph.D. from the Flinders University of South Australia in the laboratories of James McCluskey and Tom Gordon, where she studied autoimmunity in mice.

North America: Arnim Pause

Arnim Pause, for his essay "Functional Analysis of the Mammalian Cap-Binding Protein Complex eIF-4F." The essay describes his doctoral research in the Department of Biochemistry at McGill University in the laboratory of Nahum Sonenberg on the mechanisms of translation. Dr. Pause received his B.S. and M.S. degrees from the University of Konstanz, Konstanz, Germany, and is now in the Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, where he studies the von Hippel-Lindau tumor suppressor protein.